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Estudio de salud poblacional se extiende a todo el estado y abre la inscripción
The study could expand to a quarter million people, making Nevada the only state in the U.S. to offer such a program. Las Vegas, Nev. (2 de mayo de 2019) – El Healthy Nevada Project, un estudio de salud poblacional basado en la comunidad primero en su clase que combina datos genéticos, clínicos, ambientales y sociales, está ampliando la inscripción a Las Vegas. The Project aspires not only to offer genetic testing to every Nevadan interested in learning more about their health and genetic profile but ultimately, to develop and expand the Project for communities across the United States to drive positive health outcomes nationwide. Se agregarán 25,000 voluntarios del estudio en el sur de Nevada El Healthy Nevada Project anuncia extensión a nivel estatal: abre 25,000 vacantes para pruebas en Las Vegas. Ahora que el sur de Nevada abre sus puertas al estudio, el Healthy Nevada Project ofrecerá pruebas genéticas sin costo mediante una muestra de saliva simple a 25,000 voluntarios del estudio. Study volunteers will take Helix’s clinical-grade DNA saliva test and will receive their ancestry and traits, at no cost, through the My Healthy Nevada Traits app. Participants will then be given a chance to answer a follow-up health survey from Renown Institute for Health Innovation (Renown IHI), and upon survey completion, will be entered to win an iPhone. In addition, study participants can agree to be notified about genetic test results that could impact their health, and which could be used to improve their medical care. This return of clinical results, plus genetic counseling and other genetic services as appropriate, will be provided by Genome Medical, the leading network of clinical genetics specialists. Evolución y expansión continua del Healthy Nevada Project Con más de 35,000 participantes del estudio inscritos en apenas más de dos años, el Healthy Nevada Project se ha convertido en el estudio genético de más rápida inscripción del país. The Project was created by Renown IHI – a collaboration between Reno, Nev.-based not-for-profit health network, Renown Health, and the world leader in environmental data, Desert Research Institute (DRI). Leveraging Renown’s forward-thinking approach to community health care and DRI’s data analytics and environmental expertise, Renown IHI has grown its capabilities to lead a larger, more complex research study of significance that will analyze and model public health risks in Nevada and serve as a national model for future population health studies working to improve overall health through clinical care integration. En el lanzamiento piloto del proyecto el 2016 de septiembre, se inscribieron más de 10,000 miembros de la comunidad para realizarse pruebas de ADN en solo 48 horas. En marzo de 2018, en la fase dos, se les ofreció a los residentes del norte de Nevada secuenciación genómica completa mediante una simple prueba de saliva de Helix. En octubre de 2018, el proyecto anunció la devolución de los resultados clínicos a los participantes del estudio. Allí se notificaba el riesgo que tenían de padecer afecciones de Nivel 1 de los CDC, que incluyen hipercolesterolemia familiar, BRCA1 y BRCA2 positivo, y síndrome de Lynch, un precursor del cáncer de colon. These conditions affect more than one percent of the population and are inherited so they impact family members as well. Ahora, el proyecto anunció su próxima fase: la extensión de la inscripción a 25,000 personas del sur de Nevada. Serving as a National Model This expansion to Las Vegas truly makes this the “Healthy Nevada Project” with a statewide impact making Nevada the only state in the U.S. to offer such a program. “Nevada was ripe to advance population health goals because, sadly, our state ranks near the bottom in health outcomes. The Healthy Nevada Project is working to change that,” said Anthony Slonim, M.D., DrPH, FACHE, president and CEO of Renown Health and president of Renown IHI. “Nuestros investigadores están trabajando en una serie de programas clínicos y estudios científicos para determinar por qué en el condado de Washoe, el condado en el que se encuentra Renown Health, las tasas de mortalidad etarias para enfermedad cardíaca, cáncer y enfermedad crónica de las vías respiratorias inferiores de Nevada son un 33 por ciento más altas que la tasa nacional. Imagine if we can gather more data like this on a national scale and use it to change the future of health and health care? That is what the Healthy USA Project is looking to do in the years to come.” “The Healthy Nevada Project is committed to providing study participants clinically actionable data that will help improve their health,” said Joseph Grzymski, Ph.D., associate research professor at DRI, principal investigator of the Healthy Nevada Project and chief scientific officer for Renown Health. “We are providing this information at the individual level so study volunteers can make lifesaving changes to reduce their risk. We’re also doing it on the community level to develop leading-edge research on health determinants for entire neighborhoods, states and eventually, the country.” Expanding to Become the Healthy USA Project The accelerated speed of the Project is made possible thanks to the ever-decreasing cost of sequencing. Hoy en día, Helix puede secuenciar un exoma completo, lo que permite informar sobre la mayoría de los conocimientos genómicos prácticos, por una fracción de lo que habría costado hace solo 10 años. Additionally, advances in digital health mean Helix and Project researchers can capture unprecedented amounts of health data digitally, making significant contributions to advancing precision health. The partnership has managed to remove the traditional barriers of population health studies, including the difficulty in recruiting participants, establishing quality high through put lab systems, and scaling interpretation and return of results. This development will be key as other health systems around the country join the Project. “We are thrilled to see the constant, fast-paced evolution of this Project with Renown IHI,” said Justin Kao, CoFounder of Helix. “In less than a year, we have sequenced the DNA of thousands of study participants and are now preparing to offer this incredible study in other states. Combining environmental, clinical, social and genetic data allows us to discover risk factors within communities and help people take action to live longer, healthier lives. That’s what makes the next step of the Healthy USA Project so exciting for all of us. “Los detalles completos sobre la evolución del estudio y de la inscripción en el sur de Nevada se darán a conocer en un evento de prensa en Las Vegas el martes 7 de mayo a las 3 p.m. Renown Institute for Health Innovation es una colaboración entre Renown Health, una red de atención médica integrada de administración y propiedad local y sin fines de lucro que brinda servicios a Nevada, Lake Tahoe y el noreste de California, y el Desert Research Institute, líder mundial reconocido en la investigación de los efectos del cambio ambiental natural e inducido por el humano y en la promoción de tecnologías para la evaluación de un planeta cambiante. Renown IHI research teams are focused on integrating personal healthcare and environmental data with socioeconomic determinants to help Nevada address some of its most complex environmental health problems; while simultaneously expanding the state’s access to leading-edge clinical trials and fostering new connections with biotechnology and pharmaceutical companies. Obtenga más información en https://healthynv.org/. Helix es una empresa de genómica con una misión simple pero potente: to empower every person to improve their life through DNA. Our affordable, turnkey population health solution enables institutions to quickly scale projects that engage communities and accelerate research and discovery, ultimately allowing every person to benefit from the power of genomics. We've also created the first marketplace for DNA-powered products where people can explore diverse and uniquely personalized products developed by high-quality partners, providing powerful tools to increase engagement and speed the pace of population-scale genomics. Helix is headquartered in the San Francisco Bay Area, has an office in Denver, Colorado and operates a CLIA-certified and CAP-accredited next-generation sequencing lab in San Diego powered by Illumina (NASDAQ: ILMN) NGS technology. Helix fue creada en 2015. Obtenga más información en www.helix.com. Helix, el logotipo de Helix y Exome+ son marcas comerciales de Helix Opco, LLC. All other trademarks referenced herein are the property of their respective owners. Additional Media Contacts: Tracy Bower DRI 702-862-5404 media@dri.edu Eric Schubert Seismic for Helix 415-939-4366 press@helix.com
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Do You Resolve to Lose Weight and Live Healthier? Here's How.
Weight loss and healthier living tend to top most people’s lists of New Year’s Resolutions. So if you’re like the vast majority, here’s help — a comprehensive look at all of Renown Health’s programs that will help you lose weight and tackle metabolic challenges. Quick quiz: How many of the following apply to you? You have a need to lose weight, but you haven’t been guided on how to make sustainable change; You’re experienced a recent rapid weight gain, but lab tests didn’t reflect a change in your health; You’ve experienced a life-changing event that caused weight gain; You have problems with where you are carrying your weight, such as your mid-section; You’ve tried other weight loss programs, but they didn’t work. If you found yourself nodding in agreement to any one of the above statements, Renown’s programs can help. They cover the spectrum of helping with weight or metabolism challenges. But the million dollar question is: Where do you start? How to Lose Weight and Live Healthier Ideally, it’s best to start by talking with your primary care provider. Your provider knows your medical history and concerns related to your health. Talk to your provider about your past history with weight loss and gain. Your primary care provider will assist with the referral process and provide you with options you might not considered on your own. Most importantly, by starting with your primary care provider, you can take full advantage of all your health benefits. Renown offers four weight loss/management programs: Medical Nutrition Therapy Meet one-on-one with a Registered Dietitian at Renown’s Health Improvement Program to discuss your health goals. You may qualify for this program if you have: Heart or kidney disease Gastrointestinal issues Weight gain or weight loss Food allergies or sensitivities High blood pressure or high cholesterol A thyroid condition Diabetes – classes available, including: Type 2 Diabetes, insulin and gestational diabetes management during pregnancy (Offered in English & also in Spanish). For more information, call 775-982-5073. Medical Weight Management This program includes a one-on-one appointment with a board-certified bariatric doctor. You will receive a comprehensive evaluation and customized treatment plan to meet your needs and medically manage your overweight or metabolic challenges. Treatment options in this program may include nutrition changes, meal replacements, medication, exercises and also behavioral therapy. Here are a few qualifications for the program: A BMI of 25 or higher and health risk such as Type 2 diabetes, obstructive sleep apnea, cardiovascular disease, stroke, gout, osteoarthritis, infertility or polycystic ovarian syndrome A BMI of 30 and higher A metabolic problem such as diabetes, fatty liver and is not responding to regular medical care. Those with a metabolic problem may be considered normal weight, however may need to lose fat mass or reduce their waist size to get healthier. An increased risk of heart disease, stroke or Type 2 diabetes, regardless of weight that is not responding to regular medical care. For more information, call 775-982-5073. Bariatric Weight Loss Surgery We understand that the desire to have bariatric surgery is a choice you are making for your long-term health. Our team provides education on the necessary steps before, during and after surgery to ensure you are successful in controlling your obesity. You may qualify for this program if you have: A BMI of 40 or more, or: A BMI of 35 to 39.9 with significant health problems such as hypertension, high cholesterol, sleep apnea, diabetes or diagnosed arthritis To learn more, visit our Bariatric Surgery. You may also attend one of our monthly Weight Loss Surgery Seminars to learn if you are a candidate. Dietary Consultation at Renown Medical Group Many people aren’t aware that you can schedule short, frequent visits with a registered dietitian at Renown Medical Group locations in Reno or Sparks. Telehealth is also available at the Renown Medical Group – Fernley. Qualifications include: A BMI of 30 or greater You have a primary care provider with Renown Medical Group Medicare or Senior Care Plus member Since this program is only offered through Renown Medical Group, you must be an established patient. To establish with a primary care provider, call 775-982-5000. Talk to your primary care provider to see if you qualify for one of Renown’s weight management programs. Going through the referral process is the best way to ensure you are taking full advantage of your health benefits.
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Dry Weather and Your Health – What to Know
Dry weather – as northern Nevadans we know it well. Of course this doesn’t mean we’re not affected by its health impact whether you’re new to the area or are a native. Stephanie Stutz, DO, a Renown Medical Group doctor specializing in family medicine, explains how to live comfortably in the high desert. Have you noticed dry skin, itchy eyes or more bloody noses? If you call northern Nevada home, you’re probably no stranger to these problems. “We get a lot of questions from people wanting to know, ‘what can I do to prevent things from happening from the dry weather?’” says Dr. Stutz. “We do have a dry climate, and obviously in the summertime you notice it more than in the winter, so we look at things like dry skin, dry eyes and dry nose.” It generally takes about two weeks to become used to the change in climate. Dry Weather Health Tips Fortunately, there are some easy things you can do to reduce your discomfort in dry weather. Dry skin. “If you have dry skin, use a lotion without perfumes so it won’t increase the potential for drying your skin out,” recommends Dr. Stutz. For example, one home remedy for extremely dry skin (or for those with thinner skin) is cocoa butter. “It’s thicker so it goes under the skin and takes more time to absorb. As a result, you get a much more long-lasting effect.” Dr. Stutz adds. “You can also add lavender essential oil to your cocoa butter to help you sleep at night.” Dry and itchy eyes. “Use eye drops on a regular basis and keep them with you. I recommend people have a couple of bottles – one at home and one in their bag,” Dr. Stutz suggests. Dry nose. “Overall one of the best things to use is a simple nasal wash,” she says. “You can get it over the counter; it’s a saline nasal wash. Use it a couple of times each day and it can be extremely helpful. In particular, gets up into the sinuses and clears them of any pollen or residue in there.” Dry Weather Nosebleed Advice In our dry climate, you may also notice more allergies and nosebleeds. Dr. Stutz cautions, “Surely the dry air can make your allergies much worse. It can create much more irritation, pain and pressure, particularly in the nose and sinuses.” Again, Dr. Stutz recommends using a nasal wash to remove discomfort. Using a nasal wash two to three times a day can also help prevent nosebleeds. “And if you’re someone who has severe or chronic nosebleeds, you can put a little bit of Vaseline along the inside of your nose to create a moisture barrier”. Dry Weather Medication Advice In addition to allergy and nosebleed sufferers, people on certain medications may be at greater risk for symptoms in our dry climate. “The medications you are on can make you much more susceptible to drying out and becoming slightly dehydrated,” Dr. Stutz warns. For this reason discuss all of your medications with your doctor. Specifically, see if you can time them throughout the day or look at changing the dosage. Should I Get a Humidifier? Given our year-round dry weather, you may want to purchase a humidifier to help ease your symptoms. But there are some things you should know first. “You have to be careful with humidifiers as there are pros and cons,” states Dr. Stutz. “The small tabletop humidifiers are not beneficial. You need to get one covering a huge amount of square footage and holding approximately 10 to 30 gallons of water to help your home. On the negative side, if you’re not maintaining it on a regular basis, it will hold on to mold and other allergens. So the next time you turn it on, you’re actually putting that back into the air.” Do I Need to Go to the Doctor? To be sure, it’s important to know yourself and your family. If this is something you experience each year, you can try over-the-counter medications. “But remember, there’s always the caution if you’re on prescription medications,” Dr. Stutz explains. “If you are on chronic prescriptions, come in to get evaluated just to make sure you’re not using anything which interferes with your medications.” Not Just a Summer Problem As the temperatures drop, remember this isn’t just a seasonal issue here in the Reno-Tahoe area. During the winter months, our dry climate combined with cold temperatures and heaters can still cause dry skin, aggravated sinuses and even itchy eyes. So use these helpful dry weather tips all year. Comprehensive Primary Care Renown Medical Group primary care physicians provide comprehensive primary care by appointment. Doctors coordinate each patient’s medical care including checkups, immunizations, referrals to specialists, lab work, X-ray & imaging and hospital admissions. Find a Doctor
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Population Genetic Screening Show to Efficiently Identify Increased Risk for Inherited Disease
El enfoque basado en la comunidad del Healthy Nevada Project revela que hasta un 90 % de los riesgos de padecer afecciones genéticas de Nivel 1 de los CDC no se detecta cuando se usan pautas de atención clínica. In a new study published today in the journal Nature Medicine, researchers behind the Healthy Nevada Project® suggest that community-based genetic screening has the potential to efficiently identify individuals who may be at increased risk for three common inherited genetic conditions known to cause several forms of cancer and increased risk for heart disease or stroke. En 2018, el Healthy Nevada Project® (el mayor estudio de salud poblacional basado en la comunidad que combina datos genéticos, clínicos, ambientales y sociales) comenzó a notificarles a los participantes del estudio que habían dado su consentimiento sobre ciertas variantes genéticas que los predisponían a padecer las afecciones genéticas de Nivel 1 de los Centros para el Control y la Prevención de Enfermedades (Centers for Disease Control and Prevention, CDC). The study focused on identifying carriers of these conditions, which include Hereditary Breast and Ovarian Cancer, Lynch Syndrome, and Familial Hypercholesterolemia, because they are the most common conditions and early detection and treatment could significantly lower morbidity and mortality. Los resultados iniciales de casi 27,000 participantes del estudio mostraron que el 90 % de los portadores de las afecciones genéticas de Nivel 1 de los CDC no había sido previamente identificado en un entorno clínico. The authors conclude that population genetic screening would identify at-risk carriers not identified during routine care. “Our first goal was to deliver actionable health data back to the participants of the study and understand whether or not broad population screening of CDC Tier 1 genomic conditions was a practical tool to identify at-risk individuals,” explained Joseph Grzymski, Ph.D., the principal investigator of the Healthy Nevada Project®, a research professor at the Desert Research Institute (DRI), chief scientific officer for Renown Health and lead author of the study. “Now, two years into doing that, it is clear that the clinical guidelines for detecting risk in individuals are too narrow and miss too many at risk individuals.” Del grupo de 26,906 participantes del Healthy Nevada Project® que el equipo de investigación de Grzymski estudió, 358 (el 1.33 %) eran portadores de afecciones de Nivel 1 de los CDC. Sin embargo, solo el 25 % de esas personas cumplían las pautas clínicas para realizarse exámenes de detección genética. Además, más del 20 % de los portadores ya tenía un diagnóstico de enfermedad relacionada con la afección genética subyacente. “We’re at a point now where it’s possible to do clinical-grade genetic screening at population-scale,” added James Lu, M.D. Ph.D., co-founder and chief scientific officer of Helix and senior co-author of the study. “What this study demonstrates is the potential impact of doing so. By making genetic screening available more broadly, we can help the millions of Americans who are unaware that they are living at increased risk for highly actionable, genetic conditions take action.” En particular, el estudio descubrió que de los 273 participantes que eran portadores de las afecciones genéticas de Nivel 1 de los CDC y que tenían información de registros clínicos, solo 22 personas mostraron sospechas previas de tener estas afecciones genéticas subyacentes. “For the first time, we are providing information at the individual level so study participants can make lifesaving changes to reduce their risk based on their genetics,” said Anthony Slonim, M.D., Dr.PH., FACHE, president and CEO of Renown Health and co-director of the Project® study. “We’re conducting research on the community level to develop leading-edge research on health determinants for entire neighborhoods, states and eventually, the country. Returning these results allows us to understand the prevalence of genetically programmed diseases and illnesses that we have here in Nevada and ensure we are providing the best prevention and care plans. For the individual, the return of results can be life changing.” According to the CDC, early detection and intervention of the Tier 1 genetic conditions could have a meaningful potential for clinical action ability and a positive impact on public health. El Healthy Nevada Project®, que se lanzó en 2016, ofrece pruebas genéticas gratuitas a todos los residentes de Nevada, mayores de 18 años, interesados en obtener más información sobre su salud y perfil genético. Con más de 50,000 participantes del estudio inscritos en cuatro años, el Healthy Nevada Project® se ha convertido en el estudio genético de más rápida inscripción del mundo. For more about the Healthy Nevada Project® please visit healthynv.org Renown Institute for Health Innovation is a collaboration between Renown Health – a locally governed and locally owned, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California; and the Desert Research Institute – a recognized world leader in investigating the effects of natural and human induced environmental change and advancing technologies aimed at assessing a changing planet. Renown IHI research teams are focused on integrating personal healthcare and environmental data with socioeconomic determinants to help Nevada address some of its most complex environmental health problems; while simultaneously expanding the state’s access to leading-edge clinical trials and fostering new connections with biotechnology and pharmaceutical companies. Learn more at Healthynv.org. Helix is the leading population genomics company operating at the intersection of clinical care, research, and genomics. Its end-to-end platform enables health systems, life sciences companies, and payers to advance genomic research and accelerate the integration of genomic data into clinical care. Powered by one of the world's largest CLIA / CAP next-generation sequencing labs and its proprietary Exome+Ⓡ assay, Helix supports all aspects of population genomics including recruitment and engagement, clinically actionable disease screening, return of results, and basic and translational research. In response to the COVID-19 public health crisis, Helix has launched a sensitive and scalable end-to-end COVID-19 test system to meet the needs of health systems, employers, governments, and other organizations across the country. Obtenga más información en www.helix.com.