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Vaccines that provide protection against the COVID-19 virus are bringing us closer to the end of this deadly pandemic. Two different COVID-19 vaccines are currently available in the U.S. today: one from Pfizer and the other from Moderna. Kate Ward, PharmD, BCPS, Director of Clinical Pharmacy at Renown Health and Adam Porath, PharmD, Vice President of Pharmacy at Renown, share what you need to know about these vaccines. When two COVID-19 vaccines were approved by the U.S. Food & Drug Administration (FDA) in December 2020, it was cause for celebration. Why? Because according to the CDC, the vaccines are 94 percent or more effective in providing protection against the COVID-19 virus! Many people are seeking information about the new Moderna and Pfizer vaccines. Below, our pharmacy leaders provide answers to some commonly asked questions. How do the COVID-19 Vaccines Work? The Pfizer and Moderna vaccines are both mRNA vaccines that help your immune system develop antibodies against the COVID-19 virus. The vaccines use messenger RNA, or mRNA, to show our bodies’ protein-making cells how to make the spike proteins of the COVID-19 virus. Our immune system reacts to these spike proteins by creating antibodies that can recognize and destroy them. So when a person is exposed to the virus in the future, they will be less likely to get sick. What are the Differences between the Pfizer and Moderna Vaccines? The Pfizer and Moderna COVID-19 vaccines are very similar, with just a few small differences worth noting. The main difference between the two vaccines is when you should receive your follow-up dose. Patients who receive a first dose of Pfizer should receive their second dose about three weeks later. Those who receive a first dose of Moderna should receive their follow-up vaccination roughly four weeks after their first dose. People 18 years and older can receive the Moderna vaccine while people 16 years and older can receive the Pfizer vaccine. Dosage for the Moderna vaccine is 0.5 ml (100 mcg). Dosage for the Pfizer vaccine is 0.3 ml (30 mcg).

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As many people search for diets to try to achieve weight loss resolutions, Kim Colegrove, Renown Dietary Educator, has all you need to know about one of the trendiest diets – intermittent fasting. What is intermittent fasting? Intermittent fasting is an eating pattern that switches between periods of fasting with no food or very restricted caloric intake, and periods of unrestricted eating. The diet has come into popularity as a way to help people lose weight without restricting what they eat, just when they eat. How does it work? The rationale behind intermittent fasting is that the pattern of eating promotes weight loss due to hormonal changes – namely, the decrease in insulin levels – as well as effects on your gut and overall decreased energy consumption. There are various schedules, including alternate-day fasting and time-restricted feeding. For example, one popular method involves restricting your eating period to eight hours per day and then fasting for the remaining 16 hours. Another requires fasting for 24 hours once or twice per week. What should people consider before they try intermittent fasting? Some people have found success in losing weight with intermittent fasting. However, it’s important to note that it’s not a diet that necessarily promotes sustainable habits and lifestyle changes. There’s also not enough research conducted that shows its lasting impact on health, weight, or metabolic improvement. For most, an intermittent fasting diet is just that – a diet. A person will likely lose weight because they consume fewer calories, but keeping the pounds off is an aspect of healthy weight loss that requires a permanent lifestyle change. Who should NOT try intermittent fasting? Intermittent fasting is not for everyone and it can pose a health risk to women who are pregnant or breastfeeding, people with diabetes, and children and adolescents in an active growth stage. Also, it would not be appropriate for those with a history of eating disorders, as well as people with certain health conditions that require them to eat every few hours. You should always talk to your doctor before beginning a restrictive diet such as this, especially if you have a chronic health condition or are taking certain medications.

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