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Sepsis happens when a person's body reacts too strongly to an infection. Usually, our bodies fight infections with help from our immune system. But with sepsis, the body fights too hard, and that can be dangerous. Dr. Julianne Wilke, Pediatrics and Critical Care Medicine, examines pediatric sepsis's causes, symptoms and treatments and provides tips on preventing this potentially fatal condition. Most Common Causes Pediatric sepsis is a particularly concerning form of sepsis that can occur in children and infants. Therefore, it is vital for parents and caregivers to be aware of the indications of pediatric sepsis and to understand the causes. Bacterial infections are the most common cause of pediatric sepsis, accounting for over 80% of cases. Common Bacterial Causes: Staphylococcus infections (including Methicillin Resistant Staphylococcus Aureas - MRSA) Streptococcal infections (including those causing pneumonia and group B strep) Escherichia coli, or more commonly; E. coli Klebsiella and Pseudomonas infections Viral Infection Causes: Respiratory syncytial virus (RSV) Influenza Parainfluenza Adenovirus Human metapneumovirus Coronaviruses (including COVID-19) Other Causes: Fungal infections (but are relatively rare) Parasites, such as Giardia lamblia Pediatric Sepsis Symptoms Parents and caregivers need to be observant of sepsis symptoms in children and can include: Fever Extremely fast heart rate Rapid breathing Lethargy Pale or discolored skin Low blood pressure Confusion Slurred speech Abdominal pain Diarrhea & Vomiting Decreased urination Difficulty breathing Use the acronym SEPSIS: S – Slurred speech and confusion E – Extreme shivering or muscle pain/fever P – Passing no urine all day S – Severe breathlessness I – “I feel like I might die.” S – Skin mottled or discolored If any of these symptoms are present, seeking immediate medical attention is imperative.

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Seasonal Affective Disorder (SAD) is a form of depression linked to seasonal changes. Learn to recognize the symptoms of SAD in your kids (or yourself) should they appear. We checked in with Dr. Vanessa Slots, the Division Chief of General Pediatrics at Renown to help us understand this condition. 1. Blame SAD on the sun—or the lack of it Seasonal Affective Disorder is a more severe form of the “winter blues. Over-sleeping, feeling irritable or unhappy, and withdrawing from people are classic symptoms of SAD. Approximately 90 percent of people with SAD experience depressive symptoms yearly in the fall and winter, while about 10 percent have depression in the spring and summer. The causes of SAD aren’t explicitly known. Still, researchers believe it’s related to a change in circadian rhythms, with differences in the amount of sunlight during different times of the year as one factor. 2. The further north you live, the more common SAD becomes While Seasonal Affective Disorder is predominantly an adult condition, estimates are that one million children in North America have it. Interestingly, SAD does not occur in the tropics. 3. SAD is more recognizable in adults than in children Common symptoms include feeling “empty,” pessimistic, hopeless, short-tempered, restless and not knowing what to do with oneself. Symptoms vary greatly from one individual to the next. SAD is more common in women than in men. When symptoms are severe, physical examinations are required to rule out other medical causes and determine whether antidepressant medication is needed. 4. In teenagers, symptoms tend to revolve around school-related issues Schoolwork suffers, students have difficulty getting up in the morning and arriving late for class, homework is incomplete, and grades may plummet. Afflicted students have difficulty concentrating, remembering details and making decisions. They lose interest in activities that they previously enjoyed. Some teenagers tend to overeat, crave carbohydrates such as pasta and gain weight. Many teachers, school counselors and therapists should be more familiar with Seasonal Affective Disorder.

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